Cleaved-Caspase 3 p17 Polyclonal Antibody-BS80393

Cleaved-Caspase 3 p17 Polyclonal Antibody Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Sizes: 50µl, 100µl Catalogue Numbers: BS80393-50, BS80393-100 Swiss-Prot: P42574 Host: Rabbit Cleaved-Caspase 3 p17 Polyclonal Antibody-BS80393 Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Reactivity: Human, Mouse Applications: WB, All Applications: WB,1:500 - 1:2000 Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant casp