(KO Validated) Caspase-3 Polyclonal Antibody - E-AB-63602

(KO Validated) Caspase-3 Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-63602-60, E-AB-63602-120, E-AB-63602-200 Citations, Manuals and MSDS Available upon request. Abbreviation: Caspase-3 Target Synonym: CPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3 Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Mouse, Rat Application: IHC, IF Isotype: IgG Clonality: Polyclonal UNIProt ID: P42574 Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates cas