FOX04-DRI

FOXO4-DRI (FOXO4-D-Retro-Inverso Peptide) Primary Function: Senescent cell clearance, cellular rejuvenation, anti-aging research Research Use: Senolytic studies, age-related dysfunction, cancer research, tissue regeneration Molecular Formula: C130H220N42O37 CAS Number: N/A (custom research peptide) Synonyms: FOXO4-DRI, FOXO4 peptide inhibitor, Senolytic FOXO4 mimetic Description: FOXO4-DRI is a synthetic D-retro-inverso peptide designed to disrupt the interaction between the FOXO4 transcription factor and p53, a key axis that prevents apoptosis in senescent cells. By breaking this bond, FOXO4-DRI allows selective clearance of senescent cells, potentially reducing age-related tissue damage, restoring stem cell niches, and extending healthy cellular function. It has become a cornerstone in senolytic peptide research, often used in advanced anti-aging and regenerative studies. Mechanism of Action: Disrupts FOXO4–p53 binding, triggering apoptosis in senescent cells Selectively targets c