cFluor^® B548 Anti-Mouse Ly-6G (1A8)

The 1A8 monoclonal antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen1,2 and has been cited in the literature for identification of Ly-6G/Ly-6C. The antibody was conjugated to a fluorophore and purified by chromatography. PRODUCT DETAILS Clone:         1A8 Reactivity:    Mouse Format:          cFluor® B548* Isotype: