Tuberous Sclerosis Complex Report

Tuberous Sclerosis Complex Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder characterized by the onset of benign tumors in multiple anatomical sites. These neoformations include a large variety of tumor forms, which can be associated with neurological manifestations including epilepsy, autistic forms, difficulties in language and behavioral alterations. Tuberous sclerosis is divided into types 1 and 2, respectively caused by mutations in the TSC1 (10 to 30% of cases) and TSC2 (the majority of cases) genes. 2 genes analyzed It is recommended if: Genetic testing can confirm the diagnosis of Tuberous Sclerosis and is useful for identifying specific mutations. List of main conditions: Tuberous sclerosis-1 Tuberous sclerosis-2