5-LOX Inhibitor with AprèsFlex®

5-lipoxygenase (5-LOX) is a member of the lipoxygenase family of enzymes. It transforms fatty acids into leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been linked to common effects in aging individuals.1-5 Normal aging results in higher-than-desired levels of 5-LOX. The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger overproduction of arachidonic acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme. 5-LOX breaks down arachidonic acid to pro-inflammatory compounds like leukotriene B4,6 a molecule that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself modulates undesirable cell division changes.7,8 The good news is that an extract of the Indian plant Boswellia serrata has been shown to neutralize 5-LOX. Used for centuries to help with inflammatory fac