Chemical Testing Service Moisture analysis by Karl Fischer (KF) coulometric titration

Moisture analysis by Karl Fischer (KF) coulometric titration is a highly accurate and widely used technique for determining the water content in a sample. Named after its inventor, the chemist Karl Fischer, this method relies on the principle of coulometric titration to quantify the amount of water present. In this technique, the sample is dissolved or dispersed in a suitable solvent that reacts with water. The titration cell contains a reagent solution comprising iodine, sulfur dioxide, and a base, which reacts with water to produce iodide ions. The iodide ions are then oxidized at an electrode, generating an electric current proportional to the amount of water present in the sample. The coulometric titration method offers several advantages for moisture analysis, including high sensitivity, wide dynamic range, and minimal interference from other substances in the sample. It is particularly well-suited for analyzing samples with low water content or for determining moisture levels in